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JV.WVU1 V.UIIU1VU ui lilt JVwIlU ^ldUC will have taken part1 in one of the largest studies of its kind ever undertaken. Participation will be on a voluntary basis with the consent of the child’s parents or legal guardians. Final results of the evaluation study are not expected until some time in 1955.
In general, school children of the second grade will be vaccinated during a non-epidemic period and then observed during a subsequent polio epidemic to evaluate the protective effects of the vaccine. The basic factor for determining the protective effects of the vaccine will be a comparison of the incidence of paralytic polio in the vaccinated group with that of children in the first and third school grades.
In announcing the vaccine study, Mr. O’Connor emphasized that the uniqueness of the project was not merely its size. “For the past sixteen years,” he said, “millions of Americans have actively supported scientists in the laboratory helping them create this new potential weapon against polio. And now they will continue .. that cooperation and help - prove whether we have really reached our goal—the conquest of polio."
In the counties selected for the study, local physicians will administer the vaccine under the supervision of the county health officer. Members of the National Foundation’s 3,100 chapters will participate as volunteers in providing the many non-professional services required in the mass vaccinations. Other community and civic groups also will play a leading role in easing the task of vaccinating a half million or more children in hundreds of communities throughout the nation.
The two hundred or more counties to be included in the vaccine validity study are being selected mainly on the basis of a previous polio history that will provide a statistically significant result. The criteria are:
1. High polio incidence for the past five years.
2. High epidemic rate nn past five years during June through September.
86.0%